treatment-resistant depression

Ketamine for Treatment-Resistant Depression: Discover How it Helps

Depression is an insidious condition that affects millions of people worldwide, and for some, the struggle to find effective treatment can be a long and exhausting journey. Traditional antidepressants like SSRIs, SNRIs, and other medications may take weeks to show any results, and even then, they don't work for everyone. For those suffering from Treatment-Resistant Depression (TRD), the challenge can seem insurmountable. But what if there was a solution that could offer rapid relief, sometimes within hours, and could help reset the brain's pathways? At Coastline Wellness, we’re proud to offer a revolutionary therapy that’s giving hope to those who have tried everything else: Ketamine IV therapy.

What is Treatment-Resistant Depression?

Treatment-Resistant Depression is a form of depression where individuals don't experience sufficient relief from symptoms after trying multiple antidepressant medications. It affects a significant portion of the population, leaving them feeling hopeless and overwhelmed by a sense of despair. Many people with TRD also experience suicidal ideation and extreme emotional distress, making it critical to find an alternative treatment.

Enter Ketamine: A Breakthrough in Depression Treatment

Ketamine, a medication that has been used safely in hospitals for decades, is now being recognized as a powerful tool in the treatment of TRD. Traditionally known for its anesthetic properties, ketamine has shown tremendous promise in addressing mental health disorders, including Major Depressive Disorder (MDD), PTSD, and even chronic pain. But perhaps its most groundbreaking application is in the treatment of Treatment-Resistant Depression.

Unlike traditional antidepressants, which require weeks to begin working, ketamine can provide rapid relief. For many patients, improvement is noticeable within hours of their first treatment. By targeting different neural pathways in the brain, ketamine helps to reset the brain's chemistry, enhance neuroplasticity (the brain’s ability to form new connections), and restore balance in areas associated with mood regulation.

The Benefits of Ketamine Infusions

  • Rapid Relief: Ketamine offers immediate improvements in mood, often within hours to days, making it a crucial option for those in crisis.
  • Effective for Treatment-Resistant Depression (TRD): Ketamine has been shown to help individuals who have not responded to other antidepressant treatments, providing a new path to recovery.
  • Neuroplasticity Enhancement: By promoting the growth of new brain connections, ketamine helps patients break free from negative thought patterns, offering lasting emotional healing.
  • Low Risk of Addiction: Unlike many other medications used to treat depression, ketamine carries a very low risk of addiction.
  • Improved Cognitive Function and Mood: Many patients report enhanced cognitive clarity and a general improvement in their overall sense of well-being following treatment.

A Safe and Controlled Treatment Option

At Coastline Wellness, we understand the importance of patient safety. Our team of highly trained professionals administers Ketamine IV infusions in a comfortable, monitored environment. Vital signs are closely observed throughout the treatment process, ensuring that any concerns are immediately addressed.

Additionally, a chaperone is required to accompany the patient to ensure they are safely transported home after their session. This precaution ensures the overall well-being of the patient and provides peace of mind for both the patient and their loved ones.

Not Just for Depression: Ketamine's Versatility

While Ketamine therapy has proven to be an effective treatment for TRD, it also shows promise for individuals struggling with other conditions like PTSD, anxiety, chronic pain, and even traumatic brain injury (TBI). The medication helps individuals process traumatic memories, alleviate pain, and restore emotional stability. For patients suffering from chronic pain, ketamine’s analgesic properties offer significant relief by modulating pain receptors in the brain.

What to Expect from Ketamine Therapy at Coastline Wellness

At Coastline Wellness, we are committed to offering a compassionate and supportive environment for those seeking relief from mental health conditions. Our experienced team works with each patient to create a personalized treatment plan tailored to their unique needs.

Ketamine IV therapy is administered over a series of sessions, with many patients noticing improvements after their first infusion. For long-term success, we work closely with patients to monitor their progress and adjust treatment as necessary. Whether you’re struggling with depression, anxiety, or chronic pain, we are here to guide you on your journey to recovery.

Conclusion: A New Era of Hope

If you or a loved one is grappling with Treatment-Resistant Depression, there is hope. Ketamine IV therapy offers a transformative approach to mental health, providing rapid relief for those who have struggled with traditional treatments. It’s a powerful alternative for those who feel like they've exhausted all other options, and it’s available now at Coastline Wellness.

Reach out today to schedule a consultation and discover how Ketamine therapy could help you reclaim your life and your joy. You don't have to suffer in silence any longer—let us help you take the first step toward healing.


is ketamine an opioid

Is Ketamine an Opioid?

Is ketamine an opioid? In recent years, ketamine has gained significant attention as a treatment for various mental health and chronic pain conditions, but there is often confusion about whether or not it is an opioid. Let’s clarify what ketamine is, how it works, and its differences from opioids.

What Is Ketamine?

Ketamine is a powerful medication initially developed as an anesthetic in the 1960s. It has since expanded into medical fields like emergency medicine, pain management, and mental health due to its unique effects on the brain. So many might naturally ask, "Is ketamine an opioid?" Well unlike traditional opioids, ketamine does not work through the body’s opioid receptors; rather, it targets a neurotransmitter called glutamate, which is crucial for mood regulation and pain perception.

How Does Ketamine Work?

Ketamine works by blocking the NMDA (N-methyl-D-aspartate) receptors in the brain, leading to increased levels of glutamate, which in turn helps improve brain plasticity. This mechanism is essential for helping the brain “rewire” itself, making ketamine particularly effective in treatment-resistant depression, PTSD, and certain chronic pain conditions.

This process is vastly different from how opioids work, as opioids bind to specific receptors in the brain and spinal cord to dull pain and produce euphoria. While opioids can be effective for acute pain, they also come with a high risk of dependency and other side effects. Ketamine, on the other hand, does not bind to opioid receptors, meaning it has a much lower risk of dependency and provides relief through an entirely different biochemical pathway.

Ketamine vs. Opioids: Key Differences

1. Dependency and Addiction Risks:
Opioids carry a high risk of addiction due to their effects on the brain’s reward system. Ketamine, however, is considered far less addictive because it doesn’t interact with opioid receptors. In controlled therapeutic settings, ketamine is not associated with the same cycle of dependence seen with opioids.

2. Uses in Mental Health:
One of the groundbreaking uses of ketamine is in treating severe depression, anxiety, PTSD, and even some cases of bipolar disorder, particularly when other treatments haven’t been effective. This off-label use, administered under medical supervision, offers rapid relief, often within hours, whereas traditional antidepressants may take weeks. Opioids, conversely, are not recommended for mental health treatment due to their addictive potential and are generally not effective for these conditions.

3. Safety and Side Effects:
While both opioids and ketamine have side effects, they differ significantly. Opioids can lead to sedation, respiratory depression, constipation, and long-term health impacts. Ketamine’s side effects, while they may include temporary dissociation and nausea, tend to be short-lived and manageable, especially in the controlled doses used for mental health or chronic pain treatment.

Ketamine’s Role in Chronic Pain Treatment

For individuals with chronic pain, ketamine offers a promising alternative, especially when opioid treatments are either ineffective or unsuitable. Low-dose ketamine infusions have been used successfully to manage pain in conditions like complex regional pain syndrome (CRPS) and neuropathic pain. This use of ketamine allows patients to avoid the risk of long-term opioid use while still achieving pain relief, thanks to ketamine’s NMDA-receptor-blocking action, which can "reset" the brain’s pain response pathways.

Why Choose Ketamine Therapy at Coastline Wellness?

Coastline Wellness offers ketamine therapy as part of our commitment to innovative, safe, and effective functional medicine treatments. We recognize that many people are seeking non-opioid options for pain and mental health relief, and ketamine provides a promising alternative. Our experienced healthcare providers ensure that ketamine treatments are tailored to each patient’s unique needs, monitoring dosage and response closely for the safest, most effective results.

In Summary: Is Ketamine an Opioid? Nope!

In summary, the answer is clear: Is ketamine an opioid? Nope! Ketamine is a unique, non-opioid treatment that provides a safe alternative for both pain relief and mental health support. Ketamine is a distinct, versatile treatment that provides benefits for both mental health and chronic pain without the addictive risks of opioids. By targeting the brain’s glutamate system, ketamine offers a new approach to treating pain and mood disorders that traditional medications may fail to address.

At Coastline Wellness, we offer both intranasal and IV ketamine therapy options. Intranasal therapy provides a convenient, self-administered approach, while IV therapy allows for precise dosing and faster effects. Our team is here to guide you through your options with care, ensuring you receive the best treatment for your health needs. Reach out to learn more about how ketamine therapy may benefit you here.


what is ketamine for depression

What is Ketamine for Depression? How it Works

At Coastline Wellness, we understand that not every treatment works for every person, especially when it comes to mental health. That’s why we’re excited to offer ketamine for depression—a treatment that’s giving new hope to individuals who haven’t found relief through traditional antidepressants. As depression treatment evolves, ketamine for depression is leading the way, providing faster, more effective results for many patients.

What is Ketamine for Depression?

Ketamine for depression is unique in that it doesn’t work the same way as typical antidepressants. While most antidepressants target serotonin, ketamine focuses on the neurotransmitter glutamate, which is linked to mood regulation and cognition. This makes ketamine effective for those with treatment-resistant depression, a condition that hasn’t responded well to other therapies. In many cases, ketamine for depression provides relief within hours or days—a benefit that can make a world of difference for individuals in crisis.

How Does Ketamine for Depression Work?

At Coastline Wellness, we offer two primary methods of administering ketamine for depression: IV infusions and Spravato (intranasal esketamine).

  • IV Ketamine Infusions: With IV therapy, ketamine is delivered directly into the bloodstream, allowing it to reach the brain quickly. This form of ketamine for depression typically involves a series of infusions over several weeks to achieve optimal results.
  • Spravato (Esketamine) Nasal Spray: Spravato has an active ingredient of esketamine, a form of ketamine approved by the FDA as a nasal spray, provides an alternative for those who prefer a non-IV method. This form of ketamine for depression can be used alongside traditional antidepressants and is administered under medical supervision for safety.

Both methods are conducted in a safe, therapeutic environment, where our team carefully monitors patients to ensure effectiveness and comfort throughout their sessions.

Who Can Benefit from Ketamine for Depression?

Ketamine for depression has proven particularly beneficial for individuals with treatment-resistant depression. When standard medications and therapies don’t provide relief, ketamine offers a new path forward. We’ve seen many patients who, after struggling for years, experience significant symptom reduction with ketamine therapy.

Additionally, ketamine for depression can be an effective option for individuals with severe depressive symptoms, including those experiencing suicidal thoughts. Because it works quickly, ketamine can provide immediate relief and stability, which is especially valuable for those in crisis.

What to Expect at Coastline Wellness During a Ketamine Session

At Coastline Wellness, we prioritize transparency and comfort in all treatments, including ketamine for depression. Here’s what you can expect from the process:

Before the Session: During a consultation, we’ll discuss your mental health history, current medications, and treatment goals to determine if ketamine for depression is right for you.

During the Session: For IV infusions, sessions generally last around 90 minutes, including preparation, infusion, and monitoring. Patients may experience mild dissociation or a shift in perception during the session. For those using Spravato (intranasal esketamine), a similar process applies. Spravato is administered as a nasal spray in a monitored environment. This form of ketamine is FDA-approved for depression and is typically paired with traditional antidepressants. Whether using IV infusions or Spravato, our team is present throughout each session to monitor your response and ensure your safety.

After the Session: We’ll observe you for any immediate side effects before you head home. Due to the mild sedative effects of both IV ketamine and Spravato, we recommend having someone drive you home after treatment.

Are There Side Effects of Ketamine for Depression?

Most patients tolerate ketamine well though some may experience mild, temporary side effects, including:

  • Dizziness
  • Nausea
  • Slight confusion or dissociation
  • Blood pressure fluctuations

Our team at Coastline Wellness will evaluate your health history and discuss any concerns to determine if ketamine for depression is a safe option for you.

Is Ketamine Right for You?

If traditional antidepressants haven’t worked for you or if you’re seeking a faster, more effective solution, ketamine may be the answer. At Coastline Wellness, we’re here to support you on your journey to better mental health. Our experienced team will guide you every step of the way, helping you make an informed decision about whether ketamine is the right fit for your needs. Get started today by calling (910) 834-2240.


functional medicine

Functional Medicine: Getting to the Root of the Problem

When you’re feeling unwell, it’s common to seek quick relief. Conventional medicine providers often focus on treating symptoms with medications or immediate remedies. However, this approach may not address the deeper, underlying causes of your health issues. Functional medicine, by contrast, aims to identify and target these root causes, helping to restore balance to your body and reduce the need for ongoing symptom management.

What is Functional Wellness?

Functional wellness focuses on optimizing your overall health by treating the interconnected systems in your body. Functional medicine seeks to uncover and address the root causes of health concerns. This comprehensive approach, as defined by the Institute for Functional Medicine (IFM), considers your unique biochemistry, lifestyle, and environment to develop personalized care plans that promote long-term well-being.

Functional medicine ractitioners act as detectives, examining the interplay between genetics, environment, and lifestyle to understand why symptoms arise. By treating these underlying factors, functional medicine aims to provide more than just symptom relief—it works to eliminate the root causes of health issues.

The Functional Medicine Services We Offer

At Coastline Wellness, we provide a range of services designed to support your journey to optimal health. Our approach includes tailored functional medicine therapies such as Hormone Replacement Therapy (HRT), medical weight loss programs, ketamine therapy, and IV therapy. We also offer educational support to empower you with the knowledge needed to make informed decisions about your health.

  1. Hormone Replacement Therapy (HRT): Hormones are essential in regulating various body functions, from metabolism to mood. When hormone levels become imbalanced, it can lead to issues like fatigue, weight gain, and mood swings. Our HRT programs are customized to your needs, helping to restore balance and improve your quality of life.

  2. Medical Weight Loss Programs: Achieving weight loss can be complex, involving more than just diet and exercise. Our medical weight loss programs address the underlying factors contributing to weight gain, such as hormonal imbalances, metabolic issues, and emotional triggers. By taking a comprehensive approach, we help you achieve sustainable weight loss and overall improved health.

  3. Ketamine Therapy: For those battling conditions like depression, anxiety, PTSD, and chronic pain, ketamine therapy offers a promising alternative to traditional treatments. Ketamine promotes rapid synapse formation and may encourage neuroplasticity in the brain, helping to "rewire" neural circuits affected by depression and stress, according to research. This process can lead to fast and lasting improvements in mood and mental health.

  4. IV Therapy: Nutrient deficiencies can significantly impact your health and well-being. Our IV therapy services deliver essential vitamins, minerals, and amino acids directly into your bloodstream, ensuring maximum absorption and providing immediate benefits. Whether you’re looking to boost your energy, improve immune function, or enhance athletic performance, IV therapy can help. 

  5. Wellness Visits: While our other services focus on specific treatments, our Wellness Visits are designed to provide a comprehensive assessment of your overall health. These visits include detailed intake and lab testing to uncover any underlying health issues. We then offer personalized recommendations for nutrition, supplements, and medications to help you achieve optimal health. It’s important to note that Wellness Visits are an additional service, and while highly beneficial, they are not mandatory for clients using our other services.

Why Choose Functional Medicine?

Functional medicine is ideal for those who are proactive about their health and want to understand the underlying causes of their conditions. It’s particularly beneficial for individuals with chronic conditions, those who have not found relief through conventional medicine, or those who simply want a more personalized approach to their health care.

How Do I Know Which Route to Take?

Determining which functional medicine therapies are right for you begins with understanding your unique health needs. At Coastline Wellness, we guide you through this process with a detailed intake and assessment. This involves reviewing your medical history, current symptoms, lifestyle factors, and any lab results that may provide insight into your health.

Initial Consultation:

Your journey with us begins with an initial consultation, where we take the time to understand your health concerns. This consultation helps us identify potential root causes of your symptoms and determine the best course of action. We may recommend lab testing to gather more information about your body’s unique needs.

Personalized Treatment Plan:

Based on your consultation and any lab results, we develop a personalized treatment plan tailored to your specific needs. This plan may include a combination of our services, such as HRT, weight loss programs, ketamine therapy, or IV therapy. We also provide guidance on lifestyle changes, dietary modifications, and supplementation to support your overall health.

Ongoing Support:

Functional medicine is a journey, and we’re here to support you every step of the way. As you progress through your treatment plan, we’ll monitor your progress and make any necessary adjustments to ensure you’re on the path to optimal health. Our goal is to empower you with the tools and knowledge you need to take control of your health and well-being.

While functional medicine offers a unique and comprehensive approach to health, it doesn’t replace the care you receive from your primary care doctor. Instead, it complements it. Your primary care doctor is essential for managing acute illnesses and providing routine screening. Functional medicine goes a step further by addressing chronic conditions, optimizing your health, and helping you achieve a state of wellness that goes beyond just the absence of disease.

Get in Touch

At Coastline Wellness, we’re dedicated to helping you achieve optimal health through personalized care, comprehensive services, and ongoing support. Whether you’re dealing with a chronic condition, seeking to optimize your health, or simply want to take a proactive approach to your well-being, functional medicine can provide the answers you’re looking for. Get started today by calling us at (910) 834-2240.


ketamine iv therapy in wilmington nc

Why Choose Ketamine IV Therapy in Wilmington NC?

If you or a loved one are struggling with depression, anxiety, PTSD, OCD, OCPD, suicidal ideation, addiction or bipolar depression, let us offer you a glimmer of hope. Ketamine IV therapy in Wilmington, NC at our clinic can give you the relief you so desperately crave.

Our team of compassionate and experienced medical professionals have administered hundreds of ketamine IV treatments, witnessing the transformation of struggling human beings. Our chief physician associate, Chris McKinley, is a former U.S. Navy SEAL Combat Medic, understands the essence of resilience and optimization and what it takes to get people back into the game of life, feeling free from debiliating mental health conditions.

Ketamine IV therapy is one of those tools and is supported by promising research that shows it’s an option for those who have experienced limited success with conventional therapies. The results are not hearsay; they are backed by ample studies that show its effectiveness in treating pain management and several mental health conditions.

A Faster Way to Relief With Ketamine IV Therapy in Wilmington, NC

It’s true that conventional medicine options, such as antidepressant medications, can takes weeks to months to build up in your system and give you full effects, or maybe it never actually works for you. However, with ketamine therapy, you will get rapid relief, with improvements observed after just one 2-3 hour session. That means you don’t have to suffer for weeks or months to feel free from the burdens of poor mental health.

Mental health is not discriminatory and affects people of all races, genders, ages and socioeconomic status. Having a reliable tool, such as ketamine IV therapy, to help you through a chronic condition or tough times can bring the peace of mind that struggle doesn’t have to be your norm.

ketamine iv therapy in wilmington nc

What Conditions Might Ketamine IV Therapy Help With?

In the video below, our PA-C Chris McKinley dives into the benefits of ketamine IV therapy for various mental health conditions. You’ll get a behind-the-scenes look at our serene treatment room and see how you’ll be comfortably seated and relaxed throughout the session. Our clinical staff will be there to ensure your experience is both effective and supportive. Discover how this innovative therapy could make a difference in your mental health journey.

What Do I Need to Do Next?

At Coastline Wellness, you prioritize well-being and ensure a safe, comfortable environment for your ketamine IV Therapy sessions. Our experienced providers will guide you through the process, answer any questions and address your concerns, including how to pay for this life-changing treatment service. Prior to receiving ketamine IV treatment, you will meet with our practitioners to ensure it’s a good fit for you through an initial consultation, where you will receive your treatment plan. Let us help you embrace the life you deserve through our ketamine IV therapy in Wilmington, NC! Give us a call at 910.834.2240.